Autosomal dominant optic atrophy (ADOA) is a rare genetic disease that causes progressive and irreversible vision loss in both eyes starting in the first decade of life. There is currently no treatment for ADOA, which affects approximately 3 people per 100,000 worldwide.
UC Davis researchers will use a new 3.5 million grant from the National Eye Institute, part of the National Institutes of Health, to develop a nonhuman primate model of ADOA to speed the development and testing of treatments for humans.